Division of Forensic Sciences
Toxicology Section
The Division of Forensic Sciences (DOFS) Toxicology Section provides state
and local law enforcement officials and medical examiners with vital information
about human biological samples and specifically whether drugs, alcohol or poisons
may have played a role in the commission of a crime or a death.
By analyzing blood, urine, stomach contents and tissues, DOFS toxicologists
are able to establish whether traces of alcohol, drugs or poisons are present,
and if so, in what quantity.

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The Hitachi 911 analyzer is used to screen biological specimens for common drugs
of abuse.
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The Toxicology Section provides two primary services:
- Alcohol and drug testing for impaired drivers.
- Medical examiner death investigation testing.
The testing process is time consuming and begins with the receipt of a biological
sample. The sample is then assigned a unique DOFS case number and bar coded prior
to being assigned to a toxicologist for analysis. After undergoing an initial
drug screening, positive samples are extracted by a toxicologist and analyzed
using state of the art chemical instrumentation. The test data are then interpreted
by the toxicologist and the results of their analysis and conclusions are entered
into the DOFS Laboratory Information Management System (LIMS). The results and
conclusions of the toxicologist are then checked independently by another toxicologist
who has to concur with their findings. Once this step is complete an official
report is generated and released to the officer or agency that submitted the sample.
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Drugs are isolated from biological specimens through solid phase extraction. The
extraction is then analyzed by a gas chromatograph-mass spectrometer to determine
the type of drug.
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A toxicologist prepares blood specimens for analysis by a headspace gas chromatograph
for the presence of alcohol and/or drugs.
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Impaired Drivers
On average, the unit, made up of scientists and technicians, spends about 60
percent of its time working on cases involving drivers suspected of driving under
the influence of alcohol or drugs (DUI). In fact, DOFS toxicologists processed
about 10,000 traffic-related cases in 2000. While both blood and urine samples
are taken at the time of an arrest, the sample analyzed depends on the analysis
requested and the particularities of a given case. With the help of instruments
such as a headspace gas chromatograph (GC) up to 35 samples may be tested at one
time to determine the presence and the exact quantity of alcohol in a sample.
Likewise, by use of a gas chromatograph-mass spectrometer (GC-MS) minute amounts
of drugs may be detected and the exact quantity present determined as well. The
results of these tests will play a role in determining if charges will be brought
against a driver for operating a motor vehicle under the influence of alcohol
and/or drugs. By far and away the most common drugs found, after alcohol, are
cocaine and marijuana. However, date rape drugs like gamma hydroxy butyrate (GHB)
are being seen more
and more often.
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Medical Examiner Death Investigations
Similar to tests run in DUI cases, blood, urine and other bodily materials
also supply toxicologists with clues into the cause of a death. Whether a victim
was shot, stabbed or died from blunt force trauma, DOFS toxicologists are routinely
called upon to determine if drugs or poisons may have played a role in the death.
Blood, tissue and stomach contents can all provide valuable information when analyzed
with a GC-MS as to the type and quantities of drugs involved in a death. The Toxicology
section tested about 12,000 samples for drugs in 2000. |
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A toxicologist prepares to test samples submitted by the Medical Examiner's Office
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Poisons
Despite what television portrays, homicidal poisonings are rare.
Carbon monoxide is the most frequently discovered poison. Often the victims are
exposed to the deadly gas from a fire, automobile exhaust or from faulty heating
system. Other poisons routinely checked for are the "classic" poisons like cyanide,
arsenic and strychnine. These substances can sometimes be found in victims of
homicide, but more commonly encountered in suicides and accidental poisonings.
DOFS toxicologists are also capable of identifying a variety of pesticides, poisonous
plants and rare or unusual toxins. These poisons typically require an experienced
and well trained-eye to identify. The Toxicology section has scientists who specialize
in this type testing to aid in the analysis of undetermined or suspicious death
cases.
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Biological samples are prepared for Inductively Conductive Plasma/Mass Spectrometer
(ICP-MS) analysis to detect heavy metals such as arsenic.
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To test for inhalants, a volatile gas standard is collected that will be used
to compare to a biological specimen for detecting the presence of an inhalant.
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Inhalants
The Toxicology section also is responsible for identifying inhalant abuse,
such as seen by the inhalation of solvents, glues, freon and nitrous oxides. The
section receives between two to five cases involving inhalants each month, with
the majority of the victims under the age of 30 years old. In fact, a recent study
revealed one in five eighth grade students have sniffed glue or "huffed" household
product. Huffing is when an aerosol or solvent is placed in an almost closed area,
like a soda can or bag and the fumes are inhaled. Among products commonly abused
are computer and VCR cleaning solutions, cigarette lighter fluid, barbecue fuels
and correction fluid or markers. Both sniffing glue and huffing kill brain cells
and can lead to death. To determine what chemicals are present in cases where
inhalants are believed to be involved, a DOFS toxicologist uses chemical instrumentation
such as GC and GC-MS to analyze the residual air left in a lung or the chemicals
that may be found in the blood of a huffing victim.
With demands on the Toxicology section growing each day, the unit has recently
grown through the addition of 30 additional scientists to the statewide program.
The employees will be assigned to one of six toxicology labs in the state. The
other labs are located in Augusta, Columbus, Macon, Moultrie, Savannah and Summerville.
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